Follistatin 344 (FS-344) - Enhanced Pharma - 1mg × 1 vial
Buy Follistatin 344 1mg in India — Enhanced Pharma Research Grade
Follistatin 344 - Myostatin Inhibitor
→ View Follistatin 344 buying guide for IndiaNaturally occurring glycoprotein that binds and neutralizes myostatin and activin A. Studied for muscle hypertrophy via TGF-β superfamily blockade. WADA prohibited since 2019.
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Why researchers reach for Follistatin 344
Myostatin neutralization
Binds myostatin (GDF-8), preventing its suppression of muscle growth - the rationale behind follistatin's anabolic research interest.
Activin A blockade
Also neutralizes activin A - broader TGF-β superfamily antagonism beyond myostatin alone.
Satellite cell activation
Removing myostatin's suppressive signal allows satellite-cell-driven muscle expansion in animal models.
Strong gene-therapy precedent
Primate and human gene-therapy studies for muscular dystrophy demonstrated significant muscle hypertrophy and strength gains - proof-of-concept for the pathway.
Community Insights
Self-reported by pep-pedia.org users and published research summaries. Not clinical evidence.
How Follistatin 344 Works
Myostatin and activin A binding
Follistatin's extracellular domains bind myostatin and activin A with high affinity, preventing them from reaching their receptors.
ActRIIB pathway blockade
With ligands sequestered, the ActRIIB receptor on muscle cells goes unactivated - TGF-β-driven muscle-growth suppression is removed.
Hypertrophy permission
Released from myostatin's constraint, muscle satellite cells and existing fibres can expand more freely under anabolic stimuli - the mechanism behind follistatin's research interest.
Mechanism summary sourced from pep-pedia.org and the published peptide research literature.
Stack It With
Pairs Well
IGF-1 LR3
Pairs myostatin removal (the brake) with full IGF-1-receptor signalling (the accelerator) - complementary muscle-growth mechanisms in research models.
Pairs Well
MGF
Combines myostatin blockade with local satellite-cell activation - both target the satellite-cell axis but from different angles.
Full Specifications
Frequently Asked Questions
How is FS-344 different from FS-315 and FS-288?
FS-344 is the precursor that gets cleaved into the circulating FS-315 form (with a C-terminal acidic tail) or FS-288 (without). FS-315 has lower cell-surface binding and longer plasma residence; FS-288 binds cell surfaces more avidly.
Is the data mostly gene-therapy?
Yes. Pep-pedia notes most clinical follistatin research has used gene delivery (AAV vectors), not exogenous peptide injection. Injectable peptide use has limited human data and a short ~90-minute half-life that constrains dosing.
WADA status?
Follistatin has been on the WADA prohibited list since 2019. It will cause failed drug tests in athletes; use is strictly for laboratory research.
Why such a short cycle?
Pep-pedia's anecdotal protocol cycles run 10–30 days - driven by the short half-life requiring frequent dosing and limited human safety data for prolonged exposure.
Storage requirements?
Strict refrigeration. Lyophilized vials at −20°C; reconstituted vials at 2–8°C. The glycoprotein structure is more thermolabile than smaller peptides - keep cold throughout the research window.
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Follistatin 344 - Enhanced Pharma
₹10,800 · 1mg × 1 vial · Lyophilized powder + BAC water · Pan-India delivery
Add to CartResearch Use Only
This product is intended solely for laboratory and research purposes. It is not intended for human consumption, therapeutic use, or as a food or drug product. By purchasing, you confirm that this product will be used exclusively for legitimate research applications.