PT-141 (Bremelanotide) - Enhanced Pharma - 10mg × 1 vial
Buy PT-141 10mg in India — Enhanced Pharma Research Grade
PT-141 - Central Sexual Pathway Research
→ View PT-141 buying guide for IndiaBremelanotide - FDA-approved melanocortin receptor agonist (MC3R/MC4R) acting on central sexual arousal pathways. Studied for HSDD, ED, and female arousal research.
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Why researchers reach for PT-141
Central pathway action
Acts on sexual arousal pathways in the brain - mechanistically distinct from PDE5 inhibitors that act peripherally on blood flow.
Effective for both sexes
FDA-approved for premenopausal women with HSDD; also studied for male erectile dysfunction unresponsive to PDE5 drugs.
Predictable absorption
Subcutaneous route with peak ~1 hour, providing a defined window for research dosing.
No cycling needed
Unlike GH-axis peptides, PT-141 has no down-regulation pattern - used as-needed in published protocols.
Community Insights
Self-reported by pep-pedia.org users and published research summaries. Not clinical evidence.
How PT-141 Works
MC4R activation
PT-141 binds melanocortin-4 receptors (with MC3R activity) in hypothalamic regions - the central hub for sexual motivation circuits.
Central pathway cascade
Receptor activation triggers downstream dopaminergic signalling associated with arousal - distinct from vascular PDE5-inhibitor pathways.
Defined onset window
Peak plasma at ~1 hour with a 2.7-hour half-life gives a predictable research window without prolonged exposure.
Mechanism summary sourced from pep-pedia.org and the published peptide research literature.
Stack It With
Pairs Well
Gonadorelin
Different axis (HPG vs. melanocortin) - researchers studying sexual function broadly may pair central PT-141 action with HPG-axis stimulation.
Pairs Well
NAD+
NAD+ supports cellular energy and mitochondrial health - a complementary baseline for cardiovascular and metabolic research adjacent to sexual-function studies.
Full Specifications
Frequently Asked Questions
How is PT-141 different from PDE5 inhibitors?
PDE5 inhibitors (sildenafil, tadalafil) work peripherally on smooth muscle vasodilation. PT-141 acts centrally on melanocortin receptors in the brain, influencing sexual arousal pathways themselves rather than blood flow.
Why does it cause nausea?
MC4R activation has known central effects on the chemoreceptor trigger zone. Pep-pedia data shows nausea in ~40% of subjects; pre-treatment with anti-emetics 30 minutes prior is the documented mitigation.
Are there blood pressure warnings?
Yes. The FDA Vyleesi label includes a black-box warning for transient blood pressure changes. PT-141 is contraindicated for uncontrolled hypertension and cardiovascular disease research subjects. Alcohol should be avoided.
How is the 1.75 mg dose typically prepared?
PT-141 vials (10 mg) are reconstituted with bacteriostatic water (BAC water - included). The FDA label dose is 1.75 mg subcutaneous; precise volume depends on reconstitution dilution. Pep-pedia's reconstitution calculator handles the math.
Is PT-141 FDA-approved?
Yes - under the brand name Vyleesi, it is FDA-approved for premenopausal women with acquired, generalized HSDD. The research-grade peptide sold here is for laboratory use only and is not interchangeable with the prescribed Vyleesi product.
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PT-141 - Enhanced Pharma
₹5,300 · 10mg × 1 vial · Lyophilized powder + BAC water · Pan-India delivery
Add to CartResearch Use Only
This product is intended solely for laboratory and research purposes. It is not intended for human consumption, therapeutic use, or as a food or drug product. By purchasing, you confirm that this product will be used exclusively for legitimate research applications.