FOXO 4DR by Denik Pharm - FOXO4-DRI Senolytic Peptide, 10mg x 2 Vials
Buy FOXO4-DRI in India - FOXO 4DR Senolytic Peptide by Denik Pharm
The senolytic. Built to clear zombie cells.
→ Compare all FOXO4-DRI options in IndiaFOXO4-DRI is the flagship senolytic research peptide: a D-amino-acid mirror peptide that pries apoptosis-resistant senescent cells away from p53 and lets them die on schedule.
Pricing
Factory-sealed box: 10mg x 2 vials + 2ml bacteriostatic water ampoule. Ready for immediate dispatch.
🚚 Pan-India delivery / Cash on Delivery available
Research protocol reference: published senolytic protocols cite 5mg per dose, alternate days, 3 doses per cycle
Selective Senolysis
Disrupts the FOXO4-p53 interaction that keeps senescent cells alive, triggering targeted apoptosis while sparing healthy dividing cells in research models.
Landmark Aging Research
The 2017 Cell paper on FOXO4-DRI reported restored fitness, coat density and renal function in naturally aged mice, foundational senolytic literature.
Protease-Resistant Design
Built from D-amino acids in retro-inverso order: the mirror structure resists enzymatic breakdown far longer than natural L-peptides.
Cycle-Based Protocols
Senolytic research uses short pulse cycles, not continuous dosing: senescent cells are cleared in doses days apart, then the model rests.
Community Insights
Self-reported by pep-pedia.org users. Not clinical evidence.
How FOXO 4DR Works
Enters Senescent Cells
FOXO4-DRI penetrates cells and competes with endogenous FOXO4 for binding p53.
Releases p53
In senescent cells, FOXO4 normally sequesters p53 to block apoptosis. The DRI peptide breaks that grip.
Apoptosis Proceeds
Freed p53 directs the senescent cell into programmed death, clearing SASP-secreting "zombie" cells from the tissue.
Mechanism summarised from peer-reviewed literature and pep-pedia.org profiles. Contact our team for citations.
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Full Specifications
Frequently Asked Questions
What is FOXO4-DRI and what does DRI mean?
FOXO4-DRI is a synthetic peptide built from D-amino acids in retro-inverso (reversed) sequence order, a mirror image of the natural FOXO4 fragment. The design resists enzymatic breakdown while still blocking the FOXO4-p53 interaction that keeps senescent cells alive.
What are senescent cells and why clear them?
Senescent ("zombie") cells have stopped dividing but refuse to die, secreting inflammatory SASP factors that damage surrounding tissue. Their accumulation is a hallmark of aging; clearing them is the goal of senolytic research.
What protocol does the research use?
The landmark mouse work used 5mg-equivalent doses on alternate days, three doses per cycle, with cycles repeated after extended rest. Human protocols are not established; research use only.
How should FOXO4-DRI be stored?
Refrigerate at 2-8 C after reconstitution with the supplied bacteriostatic water and use within 28 days. Sealed vials store below 25 C, away from light.
Is COA available?
Yes. Denik Pharm provides batch-specific HPLC purity reports under WHO-GMP and ISO certification on request via WhatsApp or Telegram.
Ready to order?
This batch is verified. FOXO4-DRI 10mg per vial, 2 vials per sealed box.
WHO-GMP certified / ≥99% HPLC purity / Pan-India delivery / Cash on Delivery available
Research Use Only
This product is intended solely for laboratory and research purposes. It is not intended for human consumption, therapeutic use, or as a food or drug product. By purchasing, you confirm that this product will be used exclusively for legitimate research applications.